Febrile Illnesses

Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Sierra Leone in West Africa is in a Lassa fever-hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of ≈500-700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in eastern Sierra Leone. Generally only 30%-40% of samples tested are positive for Lassa virus (LASV) antigen and/or LASV-specific IgM; thus, 60%-70...

Bacteriuria in Children with Acute Febrile Illnesses.

Proteinuria in children with febrile illnesses.

was noted only in children whose fever was higher than 38 *4 'C. Selectivity studies on the protein excreted showed patterns ranging from poorly to highly selective. Initial screening for proteinuria using a dipstick method revealed a high incidence of false positives, of which only about 30% could be confirmed by the sulphosalicylic acid method. The pathophysiology of transient proteinuria in ...

Tick-borne febrile illnesses lacking specific symptoms.

We report here one case of tularemia, one case of human monocytic ehrlichiosis, and one case of febrile illness most consistent with tularemia with titers suggestive of Rocky Mountain spotted fever in residents of three south-central Missouri counties. All three cases had with nonspecific symptoms of a febrile illness. All three patients had a history of a tick bite, common in south-central Mis...

Estimating the Burden of Febrile Illnesses.

Fever without localizing features, hereafter referred to as fever or febrile illness, is among the most common reasons for persons in low-resource areas to seek health care [1,2]. The nonspecific clinical presentation of many infections that cause fever makes it difficult to distinguish one from another based on clinical history and physical examination alone. Beyond malaria diagnostics, labora...